The book is a social novel that tries to show the industrial North and its conflicts in the mid-19th century as seen by an outsider, a socially sensitive lady from the South. The story: the heroine, Margaret Hale, is the daughter of a Nonconformist minister who moves to the fictional industrial town of Milton after leaving the Church of England. The town is modeled after Manchester, where Gaskell lived as the wife of a Unitarian minister.

The change of lifestyle shocks Margaret, who sympathizes deeply with the poverty of the workers and comes into conflict with John Thornton, the owner of a local mill, also a friend of her father. After an encounter with a group of strikers, in which Margaret attempts to protect Thornton from the violence, he proposes to her, telling her that he is in love with her; she rejects his proposal of marriage, mainly because she sees it as if it were out of obligation for what she had done. Later, he sees her with her fugitive brother, whom he mistakes for another suitor, and this creates further unresolved conflict. Margaret, once she believes she has lost his affection, begins to see him in another light, and eventually they are reunited.
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